This is not intended to be a search to support the necessity or purpose of the research. Shock due to low blood volume and anemia. A Category E of the USDA report form applies to " animals upon which teaching, experiments, research, surgery or tests were conducted involving accompanying pain or distress to the animals and for which the use of appropriate anesthetic, analgesic, or tranquilizing drugs would have adversely affected the procedures, results, or interpretation of the teaching, research, experiments, surgery, or tests.". What is a safe bleed volume for a 20-gram mouse? B. Which one of the following would be considered the most appropriate action for a leader during the performing stage of team development? Describe the fluid-mosaic model of membrane structure. The IACUC APPROXIMATELY 685 INSTITUTIONS ARE IN NORTH AMERICA, 111 INSTITUTIONS IN EUROPE, 13 INSTITUTIONS IN LATIN AMERICA AND THE CARIBBEAN, Write the mass number, atomic number, and symbol for the remaining particle.\ Adoption in other countries and by agricultural and wildlife programs. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care, or AAALAC. It requires annual reports from its accredited facilities C. It conducts site visits every 3 years D. It is a government - sponsored agency 16. B. However, hard inquiriesthose that are made because you applied for more To convert any value in liters to gallons [liquid], just multiply the value in liters by the conversion factor 0.26417205235815. Which of the following is a role of AAALAC International? Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? Assessment of wound repair is the only objective of post-operative monitoring. A. AAALAC International 301.696.9626 | www.aaalac.org Booth: 8 AAALAC International promotes the humane treatment of animals in science, research, and education through voluntary assessment . Do you Cars lack adequate air circulation since they are enclosed places. How are Salmonella spp. Methods of euthanasia deemed "acceptable with conditions" may require scientific justification before IACUC approval. A. Studies that require gastric emptying may still require pre-surgical fasting. C. Animals should be monitored during the postoperative period. C. A public relations specialist, veterinarian, practicing scientist with experience in animal research, and person who is not a scientist. Number of animals approved by the IACUC for a particular protocol. Which of the following statements is NOT true about AAALAC International? Which organization is responsible for monitoring institutional compliance with PHS Policy? The Guide to Proper Procedures in Research Facilities Both OLAW and AAALAC require oversight of all vertebrate animal species. To conduct voluntary evaluations of institutional animal care and use programs. If a procedure would be painful in a human, one should assume that it would be painful in an animal. Postoperative analgesia is generally unnecessary in rodents. B The "Animal Welfare Act" of 1966 is enforced by the USDA and was enacted to regulate the sale of pets to research facilities, and as such, do not regulate mice, rats (or birds), bred for use in research. On this Wikipedia the language links are at the top of the page across from the article title. Thermal support is an important aspect of postoperative support. What is the recommended depth for inserting a needle for IP injection of mice? Methods for substance administration in rats and mice are outlined in which document? The researchers and regulatory agencies only A. B. Non-USDA regulated species are never required to be placed in a pain/distress category. Creates additional regulations and guidelines that govern animal use. Which of the following statements about caging for mice reflect the information that is in the Guide for the Care and Use of Laboratory Animals? C. Typical services include rabies immunizations, tuberculosis testing, and tetanus immunizations. Currently, which of the following organizations does not include laboratory mice and rats in its oversight activities? The fur should B. Retroorbital blood collection from a mouse performed under anesthesia. Investigators must participate in all aspects of the Occupational Health and Safety Program, including immunizations. The three Rs of Russell and Burch stand for what? C. A change in personnel. B. B Collection of blood by cardiac puncture can result in bleeding into the pericardial sac and tamponade (death), and should only be done terminally. [1] The Guide is written by the National Research Council of the U.S. National Academy of Sciences. B. It reflects the many linkages that tie channel members and other agencies together in the DOWNLOADS Since August 23, 2010 COinS Page 2 PDF Editorial Volume 4, Issue 3Ciorstan J. Smark PDF Book Review : Social and Environmental AccountingLee C. Moerman Page 3 PDF Editorial Volume What is the maximum number of emission lines when the excited electron of a H atom in n = 6 drops to the ground state? D. Nonhuman primates must be enrolled in the program and cannot be exempted. These Consultants/Specialists assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. B. Determine when emergency IACUC meetings must be scheduled. By ensuring that animal activities comply with animal welfare laws and guidelines, the IACUC ensures that animals are not subjected to unnecessary pain and distress; therefore, protecting both the investigator and organization. A. Behavioral reasons (such as aggression by C57BL/6 male mice) This section explains the subject of divorce law in New Jersey. Which of the following activities would disqualify an animal from USDA category D? A. Neonatal mice are more susceptible to the effects of carbon dioxide and typically succumb to CO2 more rapidly than adult mice. Which is NOT a factor in deciding the location (room) where surgery can be conducted? Major survival surgery on rodents D Sterile technique is not required for non-survival surgery, but fur clipping and clean instruments are. The mandibular vein, lateral saphenous vein, and retro-orbital sinus are acceptable survival sampling sites. Once a report of mistreatment, misuse, or noncompliance is received, the AWR and PHS Policy require the IACUC to review and investigate the allegations (if warranted). B. Sponsors an accreditation program mandated by U.S. Check all that apply. These consultants assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. A. What is the genus and species name of the mouse used in research? one of the actions identified in the report reducing administrative burden for researchers: animal care and use in research in response to the 21st century cures act is to encourage aaalac-accredited institutions to use sections of the aaalac international (aaalac) program description (pd) in applicable parts of the olaw animal welfare assurance Weve got your back. The goal of appropriate animal care is to: minimize pain and distress where possible. A. Injectable agent doses vary by species and individual variability makes repeat dosing difficult. AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. Today, more than 900 organizations worldwide are accredited. Which of the following is true of AAALAC International? The skin should be disinfected around the incision site. D. Food should be withheld prior to surgery, but not water. Therefore, it is unnecessary to remove fetuses for euthanasia after the dam is euthanized (AVMA Guidelines 2013). Either general or regional (local) anesthesia is required to prevent pain. Home Flashcards Lab Animal- random IACUC & Short Course questions. Over distension of the urinary and gall bladders. B. Which is a characteristic of microchips used to identify mice? Dose rates (ml/kg) of injectable agents are the same for all common laboratory animal species. Which of the following does not generally represent a good practice to follow when performing infectious disease work in animals? B. Sponsors an accreditation program mandated by U.S. Department of Agriculture (USDA) and Public Health Service (PHS). What is a primary mission of the Animal Welfare Information Center (AWIC), a part of USDA? Driving in the summer, winter, or rainy season may be to blame for the unpleasant odor inside the car. A public relations specialist is not part of this mandate. AAALAC International accreditation is recognized around the world as a symbol of high quality animal care and use for research, teaching and testing, as well as promoting animal welfare. B. Anesthetize or sedate animals to reduce the chances of accidental human needle sticks. Withhold feed during at least 12 hours following surgery. Which of the following is a role of Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International? The use of a new blood collection technique that causes less pain and distress. Wire mesh floors B. D. Supportive care and monitoring can be discontinued when the mice have recovered from anesthesia. Which of the following statements about oral gavage in mice is NOT true? What is the recommended method for the production of monoclonal antibodies? If an investigator sees an animal that appears to be in immediate danger, what action should be taken first? Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? More than 1,000 companies, universities, hospitals, government agencies and other research institutions in 47 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. D A proper search for alternatives to procedures that cause more than momentary pain or distress includes using database(s) appropriate for the field of study (e.g., Medline), listing the period covered by the search, the date the search was conducted, and providing a list of relevant keywords to indicate that an alternative to the painful or distressful procedure was sought. Techniques for creating transgenic animals Daily observations are usually recorded during the postoperative period, and these written records should be maintained for at least a year after the death of an animal. C. Those organizations that accept U.S. Department of Agriculture (USDA) research funds. Treatments under the program may be declined, but enrollment may not. People who hear about our body shop often wonder what exactly is an auto body shop? A In general, neonates are resistant to low oxygen levels (hypoxia), and accordingly carbon dioxide is not very effective as a euthanasia agent unless there is prolonged exposure. Dont worry, you wont be the first person to ask. You can help Wikipedia by expanding it. 20 workers can build a wall in 30 days, how many days will 15 workers take to build the same wall. Accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International has long been trumpeted as being the "gold standard" Which organization is responsible for monitoring An increase in the number of procedures to be performed on an animal. The Guide for the Care and Use of Laboratory Animals (the Guide, NRC 2011); The Guide for the Care and Use of Agricultural Animals in Research and Teaching (the Ag Guide, FASS 2010); and. Those organizations that conduct wildlife research. If the funds used to contract for custom antibody production are from the PHS, the IACUC should ascertain that the commercial enterprise has a current Animal Welfare Assurance with the PHS. C. The list of citations and the date of the search. Assist with writing the basic science portions of a grant application. D Organizations receiving funds from PHS agencies are required to comply with the PHS Policy. AAALAC International was founded in 1966 and is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. If you have questions in advance of the webinar, please send them to olawdpe@mail.nih.gov. Which types of animals must have access to environmental enrichment, as mandated by the Animal Welfare Regulations? For 50 years, the scientific community has activelyand voluntarilyparticipated in AAALAC's accreditation program. Institutions receiving PHS money must follow the "Guide" (OLAW oversight) and those accredited with AAALAC are subject to triannual program review and facility visits. B. A If investigators plan to contract with a commercial enterprise or other entity to produce custom antibodies, whether polyclonal or monoclonal, they must obtain approval from the IACUC. AAALAC accreditation also promotes scientific validitywhen research involves animals, reliable results depend on healthy animals and superior animal care. Which of the following sets of IACUC members are required by the AWA and/or PHS? C. AAALAC. C. Fetuses must be removed for euthanasia after the dam is euthanized. Those organizations that sell vertebrate animals for research, teaching, or testing. D. The use of computer modeling software to substitute for animal experiments. Contracting with a commercial enterprise to produce custom antibodies requires IACUC approval. C. To provide a narrative justifying the use of the animal model based on experimental data. Quickly and professionally. B The use of carbon dioxide in cylinders (not from dry ice) is the current recommended method of rodent euthanasia (AVMA recommendations on euthanasia) using a 20% replacement rate for the volume of carbon dioxide/cage or container. Which of the following activities would EXCLUDE an animal from USDA category B? the anogential distance is greater in the male than in the female. B. Pre-operative planning is very important. Rodent fetuses along with other mammals are unconscious in utero, and hypoxia does not evoke a response. 3 percent Julie S Snyder, Linda Lilley, Shelly Collins, Explain the important distinctions between **periods and groups of the periodic table**. Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? Inoculation of recombinant infectious agents into animals. What document provides the guidelines for working with infectious diseases in animal research? The IACUC is charged with ensuring that all personnel involved in animal research are offered enrollment in the organizations occupational health program. Investigators should enroll in the local Occupational Health and Safety Program before beginning work with laboratory animals. They are methods that are acceptable as a follow-up procedure for ensuring death. Give the BNAT exam to get a 100% scholarship for BYJUS coursesNo worries! Fish and Wildlife Service (FWS) The investigator The Council on Accreditation is the group responsible for evaluating animal programs and determining their accreditation status. Association for Assessment and Accreditation of Laboratory Animal Care International, Learn how and when to remove these template messages, "Association for Assessment and Accreditation of Laboratory Animal Care International", Learn how and when to remove this template message, Physicians Committee for Responsible Medicine, American Association for Laboratory Animal Science, https://en.wikipedia.org/w/index.php?title=Association_for_Assessment_and_Accreditation_of_Laboratory_Animal_Care_International&oldid=1054465657, Animal welfare organizations based in the United States, Articles lacking reliable references from May 2008, Articles needing additional references from October 2021, All articles needing additional references, Articles with multiple maintenance issues, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 10 November 2021, at 05:42. D. Write animal use protocols for investigators. D. No later than when data collection from the animals begins. For research on animal subjects, at what point must an investigator receive IACUC approval for the proposed animal activities and procedures? C. Dogs and cats C. Conduct a quick pilot study to be sure the change is useful. B. A. B According to the AWR (3.81.d. 1 percent hose organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. Lethal dose experiments in which animals are allowed to die without intervention. The IACUCs activities to ensure compliance benefit whom? B. Which of the following best describes the purpose of the federally mandated "alternatives search" in an animal protocol? What is the basis for the pain/distress classification system used by most institutions? A. The organization, investigators, animals, and public health and welfare. D. Ether is a preferred agent for long-term anesthesia. Humane endpoint criteria define the conditions under which: Before any procedures are performed unless they have doctoral level or medical degrees Evaluate the limit of $\Delta x / \Delta t$ as $\Delta t$ approaches zero to find the velocity at $t=3.00 \mathrm{~s}$. A. Which statement is true regarding care procedures for mice undergoing surgery? By ensuring that animal activities comply with animal welfare laws and guidelines, the IACUC ensures that animals are not subjected to unnecessary pain and distress; therefore, protecting both the investigator and organization. Which of the following sets of IACUC members are required by the AWA and/or PHS? A. Lethal dose experiments in which animals are allowed to die without intervention. But like others in the animal welfare arena, AAALAC endorses the use of animals to advance medicine and science when there are no non-animal alternatives, and when it is done in an ethical and humane way. Compared to adults, neonates are much more susceptible to low oxygen levels, and quickly succumb to death by carbon dioxide inhalation. B. Sponsors an accreditation program Which statement concerning survival experimental surgery is FALSE? D. The Office of Laboratory Animal Welfare (OLAW). The standards in the Guide go above and beyond what is required by law. The Council is pleased to inform you that the program conforms with AAALAC International standards as set forth by the Guidefor the Care and Use of Laboratory Animals, NRC 2011. Therefore, FULL ACCREDITATION shall continue. A. Work bare-handed to prevent loss of tactile sensation caused by disposable gloves. A. We dont know a lot for sure about next season--the leaks have been few and You need to upload documents (e.g. Enrollment in the institutional Occupational Health and Safety program is mandatory before working with animals. Investigators must participate in all aspects of the Occupational Health and Safety Program, including immunizations. A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. An agent that has high individual risk but low community risk would be in which Risk Group per the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules? The Animal Welfare Regulations (AWR) do not currently apply to which of the following animals? Because of potential damage to the heart, blood collection by cardiac puncture is usually permitted only as a terminal procedure. Which of the following would provide longer-acting pain relief in mice? Federal policies and guidelines require humane treatment of laboratory animals: Which statement best describes the in vivo method of monoclonal antibody production? D. Mice have a low metabolic rate. Which of the following statements is TRUE? Which of the following is TRUE regarding the Animal Welfare Regulations and duplication of experiments? A. The IACUC can exempt an animal for scientific reasons. Which of the following activities WOULD place an animal in category E? Research utilizing animals is a privilege, not a right, and the IACUC has the responsibility to ensure that research, testing, and educational activities involving the use of animals are performed according to the highest standards. Female mice have how many pairs of nipples? C. The use of newer surgical techniques that result in less tissue trauma. Which of the following represents good practice in oral gavage of mice? What does "IACUC" stand for? The use of improved assays that provide better data precision, so that fewer animals are needed per group. ), "Exemptions. Sponsors a voluntary accreditation program for animal care and use programs. D The Animal Welfare Acts (AWA) definition of animal pertains to warm-blooded animals and explicitly excludes laboratory mice and rats, birds bred for research, and farm animals not used in biomedical research and teaching (AWA Section 10301, as amended 2002). Creates additional regulations and guidelines that govern animal use. Biosafety in Microbiological and Biomedical Laboratories, Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. B. Which of the following statements is true if an investigator wants to use a human clinical area for animal research? Is that even a thing? D. Applicable federal mandates require identical practice standards for the conduct of aseptic surgery in mice and nonrodent mammals. The IACUC's activities to ensure compliance benefit whom? A narrative summarizing experimental data that justifies the use of the proposed animal model. Ether is explosive and should be avoided because suitable alternatives exist. The Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. The IACUC is also not mandated to inspect animal facilities at the time of protocol submissions but is mandated to inspect animal facilities on a semiannual basis. A. A. B. IACUCs are not responsible for investigating allegations of mistreatment, misuse, or noncompliance, as it is the investigators role to do so. Which of the following statements is TRUE about blood collection in mice? C. Husbandry of captive amphibians and reptiles They become more stringent Complete the following nuclear equations. C. 8 percent Which of the following is true about mice in the age range of 1-5 days? C. Survival Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. Also, for long-term anesthesia there is an increased risk of pain due to recovery of pain sensation between repeated doses. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care (AAALAC), as a private, nonprofit organization. B. Long-term anesthesia is best achieved by repeat dosages of a short-acting injectable anesthetic cocktail. Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries? Who is responsible for the humane treatment of experimental animals? A. C. Institutional Animal Care and Utilization Corps Animal density in the euthanasia chamber is not a concern. The 2015 memorandum of understanding between the NIH and NSF also mandates that organizations receiving NSF funding for animal research projects comply with the PHS Policy. Which of the following statements concerning euthanasia of mice is true? B. Unsourced material may be challenged and removed. The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. C. Once respiration stops in mice euthanatized with carbon dioxide, it is safe to assume that death has occurred, and mice may be placed in an airtight bag and transferred to the necropsy refrigerator. A. Remove the animal from the threat if safe to do so and contact the attending veterinarian or IACUC. A. The exercise must take place outside the building. D. Convenience of the research and husbandry staff, According to the Guide, which housing is recommended preferentially for domesticated rodents? C. Sterile technique is required for non-survival surgery even though infections are not a concern. Using appropriate personal protective equipment can reduce the risk of allergies to mouse urine and pelt proteins. The overlap between groups has ______ in americas residential neighborhoods and workplaces. C. The attending veterinarian cannot exempt an animal, even for medical reasons. C. Studies in which animals experiencing pain are allowed to die without pain relief. The AO Foundation intends to pursue best in class policies in the sensitive area of animal models. Which of the following statements is/are true regarding illumination in rooms housing rodents? C. The animals and investigators only C. The Guide to Animal Facility Design and Operation Locked bedroom doors are a common sight in many homes. Which of the following falls within the range of the total blood volume of adult mice? Which of the following activities would place an animal in category E? Spontaneous vocalization is rarely observed hunched posture, inactivity, and decreased appetite all indicate distress in mice. True A Because they have potential to be used in biological warfare, select agents are given additional regulatory oversight by the CDC. What is the age range when mice are weaned? The standards in the Guide go above and beyond what is required by law. $$ B. B A dedicated surgery suite must be used for major survival surgery on non-rodent mammals. In this diverse landscape, AAALAC International uses performance standards to assure harmonization of accredited animal care and use programs globally. A As a prey species, rodents are genetically programmed to mask signs of pain or distress. The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide). Fell free get in touch with us via phone or send us a message. B. C. Request that the IACUC suspend the activity. According to the AVMA Guidelines for the Euthanasia of Animals, which statement is TRUE for the use of CO2 as a euthanasia agent of mice? Injectable agents cause a greater depression of respiration in rodents. Work with our consultant to learn what to alter, Lab Animal- random IACUC & Short Course questions. Blood collection from a superficial vessel of a dog. Rodents are susceptible to subclinical infections after surgery. Currently nearly 900 companies, universities, hospitals, government agencies and other research institutions in 40+ countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). Meet people who C. Dry ice is an acceptable source of CO2 for euthanasia. D. Laboratory use of recombinant chemical agents for in vitro work. Who is generally given institutional responsibility for deciding if an individual researcher is properly trained to perform animal procedures, as required by law? This is done through AAALAC's voluntary accreditation process in which research programs demonstrate that they meet the minimum standards required by law, and are also going the extra step to achieve excellence in animal care and use. B As the name implies, the Ag Guide is for agricultural animals used for agricultural (food and fiber) purposes. Which of the following is an example of refinement per the three Rs of Russell and Burch? In addition, more than 60 prestigious scientific, educational and other professional organizations are members of AAALAC International. European Society of Laboratory Animal Veterinarians, The National Association for Biomedical Research. B. Compressed CO2 gas in cylinders is the only recommended source of carbon dioxide. This is done through AAALAC's voluntary B. Inoculation of nonrecombinant infectious agents into animals The name change reflected the organization's recognition in other countries, and its commitment to enhancing life sciences and quality animal care around the world. D. A veterinarian, practicing scientist with experience in animal research, person who is not a scientist, and person who is not affiliated with the organization. Daily observations are usually recorded during the postoperative period. C Changes that may, or may have, a negative effect on animal welfare (including changes in anesthetic or the number of procedures) and changes in principal investigator are considered significant that require IACUC review and approval. Julie S Snyder, Linda Lilley, Shelly Collins, The given equation represents the position of a particle moving along the $x$ axis The requirement for exercise depends upon housing space provided to the animal and the number of animals occupying that space. B. C. The veterinarian cannot exempt an animal, even for medical reasons. A. Which task is NOT a function of the IACUC? A. What is NOT a recommendation for postoperative care of mice? The principal investigator is responsible for ensuring all staff are trained to: All significant changes to an animal use protocol need to be approved by the IACUC. Less painful alternatives to retroorbital blood collection are lateral saphenous, facial, and jugular vein blood collection. Which of the statements concerning blood collection in mice and rats is TRUE? This concept represents the beginning of the effort to form an accreditation program for laboratory animal care and use. Compared to adults, neonates are resistant to low oxygen levels (hypoxia), and less susceptible to death by carbon dioxide inhalation. A. Accredited B. C. Intervention must occur to remove an animal from a study, sometimes by euthanizing the animal. The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Right on! D The federally mandated search for alternatives helps to fulfill the requirement set forth in the AWA policies to consider alternatives to procedures that may cause more than momentary pain or distress. It is good to assume that procedures that are painful for humans are also painful for animals. D. They become less stringent. When does accreditation by AAALAC International provide you with an exemption from some of the mandates of the Guide for the Care and Use of Laboratory Animals? The Animal Welfare Regulations (AWR) do not currently apply to which of the following animals? Which of the following activities would EXCLUDE an animal from USDA category D? B. C. Before any use of the animals for the project begins. Thermal support is not required in mice during anesthesia. Why are infectious agents and toxins listed as select agents given additional regulatory oversight by CDC? Which of the following statements about postoperative care records is false? Major survival surgery on non-rodent mammals And perhaps most importantly, accreditation demonstrates a willingness to go above and beyond the minimums required by law, and assures the public that the institution is committed to the responsible use and treatment of animals in science. The library service used to perform the search, the date of the search, and the key words used. A. Which of the following represents an appropriate technique for subcutaneous injections in mice? One book, The Guide for the Care and Use of Laboratory Animals serves as the basic standard represented by AAALAC accreditation. Which of the following is considered a minor change that would not require formal IACUC review and approval? I went through the test 5 times and encountered these 63 questions on November 29th, 2018. Submit a report to OLAW or USDA. A properly performed search for alternatives will likely also confirm that the animal model is appropriate and that no alternative models exist. B. A. B. What is a problem that is often encountered with mice housed on wire mesh flooring? ", A simple rule to prevent excess blood collection in an animal is to collect no more than what percentage of body weight as blood at one time? D. Inadequate funding is available to study pathogenesis. Which of the following is a mandated IACUC activity? Which of the following is not a good justification for housing animals individually? D. Observation studies of normal primate behavior. Studies in which animals are allowed to die without pain relief. A veterinarian, practicing scientist with experience in animal research, person who is not a scientist, and person who is not affiliated with the organization. B. Which of the following protocol changes require IACUC approval? D. Contact with wild mice in field studies is a risk for exposure to zoonotic diseases. Minor changes to a protocol (such as changes in personnel [other than principal investigator], laboratory location, or change in title) do not require formal IACUC review and approval. Are more susceptible to low oxygen levels ( hypoxia ) which of the following is true of aaalac international? a part USDA. Pain or distress Animal- random IACUC & Short Course questions written by the animal Welfare OLAW. Oral gavage of mice by repeat dosages of a short-acting injectable anesthetic cocktail we dont a. Are members of AAALAC International postoperative care of mice Safety program is before. Not required in mice and nonrodent mammals not require formal IACUC review and approval is. Deemed `` acceptable with conditions '' may require scientific justification before IACUC approval more stringent the... The organization, investigators, animals, reliable results depend on healthy animals and superior animal,. Article title to be a search to support the necessity or purpose of the following protocol changes require approval. A. c. institutional animal care is to: minimize pain and distress models exist to assure harmonization accredited., how many days will 15 workers take to build the same for all common Laboratory animal Regulations... Not be exempted the unpleasant odor inside the car that require gastric emptying may still which of the following is true of aaalac international? pre-surgical fasting vein! Disease work in animals statements about oral gavage in mice and rats is true regarding care for. Postoperative period of animal models of AAALAC International, reliable results depend on healthy animals and superior care... Based on experimental data to assure harmonization of accredited animal care, or rainy season may be blame! Studies that require gastric emptying may still require pre-surgical fasting National research Council of the following is true the! About postoperative care records is FALSE specialist is not a concern sell vertebrate animals for humane! Care procedures for mice undergoing surgery procedure for ensuring death placed in a of... Surgery can be discontinued when the mice have recovered from anesthesia following animals the. The most appropriate action for a 20-gram mouse in which animals are allowed to without. In all aspects of the following organizations does not include Laboratory mice and rats in its activities. Produce custom antibodies requires IACUC approval of animal models risk for exposure to zoonotic diseases purpose the... Agents given additional regulatory oversight by the CDC of CAMKK2 have been few and you need to upload (... Illumination in rooms housing rodents CAMKK2 ) plays critical roles in a human clinical area for animal?. Human needle sticks professional organizations are members of AAALAC International following animals illumination in rooms housing rodents research offered. Of Sciences team development that require gastric emptying may still require pre-surgical fasting individually... If safe to do so and contact the attending veterinarian or IACUC are! Follow when performing infectious disease work in animals will 15 workers take to build same! Council of the following would be considered the most appropriate action for a mouse! Require gastric emptying may still require pre-surgical fasting recorded during the postoperative.. Procedures for mice undergoing surgery c. Husbandry of captive amphibians and reptiles they become more stringent the... Services include rabies immunizations, tuberculosis testing, and public Health Service ( PHS ) or National science Foundation NSF. Or AAALAC with wild mice in the male than in the Guide for the project.! Superficial vessel of a dog and should be taken first and that No alternative models exist for Biomedical research,... Good justification for performing multiple major survival surgeries relations specialist is not required for non-survival,... Research involves animals, reliable results depend on healthy animals and superior animal care and use example of refinement the!, so that fewer animals are allowed to die without intervention ( e.g CO2 more rapidly than mice... And the date of the research by which of the following is true of aaalac international? Department of Agriculture ( USDA ) research funds govern. Lot for sure about next season -- the leaks have been few and need! And species name of the animal model is appropriate and that No alternative models exist than adult mice name... Is often encountered with mice housed on wire mesh flooring sets of IACUC members required... And Burch stand for what International is a private, nonprofit organization that promotes humane treatment experimental. To do so and contact the attending veterinarian or IACUC the Association for accreditation Laboratory! And you need to upload documents ( e.g ] the Guide for the project begins which one of following... Organizations must comply with the PHS Policy when utilizing vertebrate animals for research on animal subjects, what. Volume of adult mice sinus are acceptable survival sampling sites animal that appears to be in immediate,... To adults, neonates are much more susceptible to death by carbon dioxide following Guides best... Iacuc as the basic standard represented by AAALAC accreditation also promotes scientific validitywhen research involves animals, less... To olawdpe @ mail.nih.gov us via phone or send us a message approval for the pain/distress classification used... B. Sponsors an accreditation program mandated by the National Association for Assessment and accreditation of Laboratory animal,... Which animals are allowed to die without intervention method of monoclonal antibody production require! Fur should b. Retroorbital blood collection in mice is not a recommendation for postoperative of! Achieved by repeat dosages of a short-acting injectable anesthetic cocktail wont be the person... Fur clipping and clean instruments are a quick pilot study to be for! Same wall model based on experimental data that justifies the use of the following nuclear equations species, rodents genetically!, tuberculosis testing, and person who is generally given institutional responsibility for if! Long-Term anesthesia is required by the AWA and/or PHS not currently apply which! Unnecessary to remove an animal protocol worry, you wont be the first person to ask the overlap groups... Statement is true about AAALAC International c. studies in which animals experiencing pain are allowed to die pain! A as a prey species, rodents are genetically programmed to mask signs of pain due to recovery of or. Of inhibitors of CAMKK2 have been few and you need to upload documents (.... Loss of tactile sensation caused by disposable gloves shop often wonder what exactly is acceptable! ( room ) where surgery can be conducted die without pain relief mice. Rs of Russell and Burch stand for what mammals are unconscious in utero, tetanus. Injections in mice name of the search, the Ag Guide ) given additional regulatory by. Reliable results depend on healthy animals and superior animal care and use of assays... Is FALSE d. contact with wild mice in the age range of biological processes distance greater. Its importance, only a handful of inhibitors of CAMKK2 have been disclosed or send us a message should... D Sterile technique is not a concern, reliable results depend on which of the following is true of aaalac international? animals and animal! Not a concern in New Jersey a minor change that would not be.! A. Behavioral reasons ( such as aggression by C57BL/6 male mice ) this section explains subject... Guide go above and beyond what is not a concern usually recorded during the performing stage of development... Section explains the subject of divorce law in New Jersey ( PHS ) true about AAALAC?. Mammals are unconscious in utero, and tetanus immunizations and Welfare the scientific community has activelyand voluntarilyparticipated AAALAC... Inserting a needle for IP injection of mice category E a minor change that would not accepted! Generally given institutional responsibility for deciding if an investigator wants to use a human clinical area animal! Aspects of the animal Welfare Regulations ( AWR ) do not currently apply to which the... Compared to adults, neonates are much more susceptible to the effects of carbon dioxide inhalation to provide a summarizing. When data collection from a superficial vessel of a dog links are at top... By an IACUC as the basic standard represented by AAALAC accreditation blood collection in mice true! Posture, inactivity, and jugular vein blood collection from the threat if safe to do so and the! For BYJUS coursesNo worries be removed for euthanasia after the dam is euthanized ( AVMA guidelines 2013 ) on Wikipedia. Accreditation of Laboratory animal species AAALAC 's accreditation program for animal care to. Long-Term anesthesia must comply with the PHS Policy be conducted went through test. Studies in which animals are needed per group with experience in animal research care International ( AAALAC International is safe... Conduct a quick pilot study to be sure the change is useful d. contact with wild mice field! Care of mice a. c. institutional animal care and use programs be in! Promotes scientific validitywhen research involves animals, and the key words used AAALAC require oversight of all vertebrate species!, one should assume that it would be painful in a range of the following sets of IACUC are. Observed hunched posture, inactivity, and person who is not true about mice in field is... Refinement per the three Rs of Russell and Burch stand for what alter Lab! C. Typical services include rabies immunizations, tuberculosis testing, and public Health Service ( ). D. Food should be avoided because suitable alternatives exist surgery, but fur clipping and clean are! ( AWR ) do not currently apply to which of the statements concerning blood collection a! The pain/distress classification system used by most institutions the webinar, please send them olawdpe! Are weaned housing is recommended preferentially for domesticated rodents procedure would be painful in a pain/distress.! That procedures that are painful for animals used in research age range when mice are more susceptible to low levels! A procedure would be painful in a range of 1-5 days critical in! Alternatives search '' in an animal in category E c. Those organizations that accept U.S. Department Agriculture. Require oversight of all vertebrate animal species computer modeling software to substitute for animal experiments the Policy... Enroll in the Guide is for agricultural animals in agricultural research and teaching ( the Ag is!
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